Can GLP-1s Save America's Healthcare System?

David Ricks, Chair and CEO of Eli Lilly, joins Scott to discuss the rise of GLP-1 drugs, the future of obesity treatment, and why America's healthcare system is facing a crisis of trust. They explore healthcare costs, addiction, unregulated peptides, pharmaceutical innovation, and the role AI could play in the next generation of drug discovery.

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Timestamps
00:00 - In This Episode
01:14 - Can you tell us about Eli Lilly?
02:41 - Why are GLP-1s such a breakthrough, and where do they go next?
05:01 - How much of America’s fiscal challenge is ultimately an obesity problem?
07:04 - What are some other applications of GLP-1s beyond reducing obesity?
10:25 - Can GLP-1s reduce cravings beyond food, including alcohol?
13:19 - How do you reconcile shareholder returns with broader access to GLP-1s?
19:38 - Ad Break
22:28 - Can you talk about the peptide craze, and what they’re used for?
27:18 - What explains Lilly’s outsized success relative to its pharma peers?
33:30 - How is Lilly using AI, and what impact will it have on drug discovery?
38:43 - Ad Break
41:04 - What advice would you give your 25-year-old self?
44:02 - What’s your advice for raising boys?
47:08 - What’s your guilty pleasure?
47:19 - What’s the last piece of media you watched that stayed with you?
47:39 - What do you think you'll look back on as the best chapter of your life?
47:57 - What person has had the biggest impact on your life?
48:05 - How has losing your father changed the way you approach fatherhood?

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